Product Information
Protein full name | Proliferation marker protein Ki-67 |
Synonyms | MKI67, marker of proliferation Ki-67, KIA,MIB-1, PPP1R105 |
Immunogen | KLH conjugated Synthetic peptidecorresponding to Human Ki67 |
Uniprot ID | P46013 |
Isotype | IgG1,κ |
Purity | Affinity purification |
Subcellular location | Nucleus |
Applications
IHC/IF | Human, Mouse, Rat | 1: 300-1: 600 |
ICC/IF | Human, Mouse, Rat | 1: 100-1: 500 |
Background
equired to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly . Associates with the surface of the mitotic chromosome, the perichromosomal layer and covers a substantial fraction of the chromosome surface . Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility .
Storage
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
0574-6262-1777